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pylori and N-methyl-Nnitro-Nnitrosoguanidine (MNNG), the downstream pathways P53, Wnt, Ras, and mTOR are activated by ROS ( via ROS-triggered ER stress, and promoting the development of gastric cancer ( H pylori CagA produces cells with oxidative DNA damage by inducing spermine oxidase (SMO), and a portion of these cells are apoptosis-resistant and therefore highly susceptible to developing cancer ( H pylori infection

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Our results concluded that i) intracellular GSH is associated with antibiotic susceptibility, ii) extracellular GSH exhibited antibacterial activity regardless of antibiotic susceptibility and resistance, iii) the antibacterial activity of GSH synergistically enhanced susceptibility of conventional antibiotics, and iv) GSH-mediated acidity was partially associated with the antibacterial activity of GSH